Prospects for hormone replacement therapy in postmenopausal women

The first track in the short term would be to study the relative merits of different dosages of substitution treatment and various forms of administration of estrogen or progesterone is currently available. The action of estrogen, like any medicine, is extremely dependent on the dose used and its mode of administration. However, studies published to date have used one type of assay in a single combination. In addition, the hormones used in U.S. studies differ from those usually use in Europe.

Note that in the well-known case of the contraceptive pill, the decrease in the dosage of steroids, and the changing nature of the hormones used have helped over the years to reduce the risk to make them quite acceptable, both from the point of view that financial point of view in public health.

The second track, for the longer term, is to continue research efforts to understand fundamental mechanisms of action of steroid hormones in different target tissues such as endometrium, vaginal mucosa, the lining of the vessels, the liver or bone.

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